Searchable abstracts of presentations at key conferences in endocrinology

ea0065p244 | Metabolism and Obesity | SFEBES2019

Hepatic steatosis in rats with dexamethasone-induced metabolic syndrome: a role for Ocimum gratissimum leaf extract

Shittu Shehu-Tijani , Adeoye Tolulope , Shittu Seyyid , Lasisi Taye

Ocimum gratissimum (OG) was shown to reverse dyslipidemia in diabetes mellitus. The present study investigates the effect of OG on hepatic lipid synthesis in animals with metabolic syndrome induced by dexamethasone. Twenty male Wistar rats (130 ± 20 g) were randomly grouped into four (n=5 each) as control, normal+OG, Dex and Dex+OG. Dexamethasone (1 mg/kg) was administered intraperitoneally to Dex and Dex+OG groups followed by normal saline and OG (400 m...